新型冠状病毒抑制剂_瑞德西韦_【天津范德生物】|奶爸SEO黑帽技术

新型冠状病毒抑制剂_瑞德西韦_【天津范德生物】

奶爸SEO • 2016年7月29日上午11:40 • SEO入门

瑞德西韦NMR and HPLCCOA
Names：Remdesivir
CAS号： 1809249-37-3MDL Number： NA
MF(分子式)： C27H35N6O8PMW(分子量)： 602.6g/mol
EINECS:NAReaxys Number:NA
Pubchem ID:121304016Brand:BIOFOUNT

中文别名GS5734，瑞德沙韦英文别名Remdesivir; GS-5734; GS 5734; GS5734, Prodrug of GS-441524; Prodrug of GS441524; Prodrug of GS441524;CAS号1809249-37-3SMILESCCC(CC)COC(=O)C(C)NP(=O)(OCC1C(C(C(O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4Inchi暂无数据InchiKeyRWWYLEGWBNMMLJ-YSOARWBDSA-N分子式 Molecular WeightC27H35N6O8P分子量 Formula602.6g/mol闪点 FPNA熔点 Melting pointNA沸点 Boiling pointNA物理属性 Physical propertypowder密度 DensityNA蒸汽压 Vapor PressureNA储藏条件 Storage conditionsDry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).溶解度Solubility化学性质CharactersSolid powder存储条件StorageDry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).产品说明瑞德西韦Remdesivir (GS-5734) 是一种核苷类似物,具有抗病毒活性。IntroductionRemdesivir has been found to show reasonable antiviral activity against more distantly related viruses such as respiratory syncytial virus, Junin virus, Lassa fever virus, and MERS-coronavirus.Application1瑞德西韦的用途1：最新研究表明瑞德西韦可作为新冠状病毒的先导化合物作为新型冠状病毒新药研发在科研中使用。Application2瑞德西韦的用途2：之前研究证明瑞德西韦具备治疗埃博拉病毒的功效。Application3 瑞德西韦Remdesivir (GS-5734) ，CAS号：1809249-37-3 是一种核苷类似物，具有抗病毒活性，在 HAE 细胞中，对SARS-CoV和MERS-CoV的EC50值为 74 nM，在延迟脑肿瘤细胞中，对鼠肝炎病毒的EC50值为 30 nM，瑞德西韦是最新抗新型冠状病毒的主要成分，目前仍在临床研究过程中。瑞德西韦Remdesivir (GS-5734) is a nucleoside analogue, with effective antiviral activity, withEC50s of 74 nM forSARS-CoVandMERS-CoVin HAE cells, and 30 nM formurine hepatitis virusin delayed brain tumor cells.

Remdesivir has been found to show reasonable antiviral activity against more distantly related viruses such as respiratory syncytial virus, Junin virus, Lassa fever virus, and MERS-coronavirus. GS-5734 was rapidly pushed through clinical trials due to the 2013–2016 West African Ebola virus epidemic crisis, eventually being used in at least one human patient despite its early development stage at the time. Preliminary results have been promising, and further clinical trials are planned.

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新型冠状病毒抑制剂_瑞德西韦_【天津范德生物】

瑞德西韦NMR and HPLCCOA

Names：Remdesivir

CAS号： 1809249-37-3MDL Number： NA

MF(分子式)： C27H35N6O8PMW(分子量)： 602.6g/mol

EINECS:NAReaxys Number:NA

Pubchem ID:121304016Brand:BIOFOUNT

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